Robert B. Grossman | ��ɫ��Ƶ College of Arts & Sciences

Robert B. Grossman

Professor of ��ɫ��Ƶ

If you are interested in joining the graduate program in ��ɫ��Ƶ at the ��ɫ��Ƶ, please send all correspondence to the Director of Graduate Recruitment, dgr.chemistry@uky.edu. I have no role in admissions into the graduate program.

Please click one of the tabs below for a description of my research program, my efforts in chemistry pedagogy, and a list of my publications.

Contact Information

robert.grossman "at" uky.edu

321 ��ɫ��Ƶ-Physics Building

859-257-1285

Education

A.B. in ��ɫ��Ƶ, Princeton University, 1987
Ph.D. in Organic ��ɫ��Ƶ, Massachusetts Institute of Technology, 1992

Research Interests

Synthetic Organic ��ɫ��Ƶ
Biosynthesis

Affiliations

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Organic

Research

Our group develops new synthetic methods and applies them to the synthesis of natural products and biologically relevant compounds. Students learn skills that prepare them for employment in the pharmaceutical and contract synthesis industries.

We have developed two new methods for the 1,2-diamination of alkenes. We are also exploring new total synthetic routes to loline using one of these methods.

New Pedagogy

As a service to the research community, I have created an of all of the polycyclic polyprenylated acylphloroglucinols (PPAPs) discovered to date.

I am the author of , an intermediate-level textbook for advanced undergraduates and beginning graduate students.

I am also a creator of , a Web-based program for organic chemistry homework that guides students to the correct answer without giving away the answer.

Selected Publications

Selected Publications:

Research papers from independent career:

Juan Pan, Eliott S. Wenger, Chi-Yun Lin, Bo Zhang, Debangsu Sil, Irene Schaperdoth, Setareh Saryazdi, Robert B. Grossman, Carsten Krebs, and J. Martin Bollinger, Jr. "" 2024, , 1674.
Yu-Feng Qiu, Robert B. Grossman, and Xing-Wei Yang. "." 2023, , 2391.
Sailajah Gukathasan, Oluwatosin Obisesan, Setareh Saryazdi, Libby Ratliff, Sean Parkin, Robert B. Grossman, and Samuel Awuah. "" 2023, , 13118.
Yang Luo, Robert B. Grossman, Xiao-Bin Nie, and Xing-Wei Yang. "" 2023, , 6215.
Setareh Saryazdi, Sean Parkin, and Robert B. Grossman. "" 2023, , 331.
Zhi-Hong Xu, Robert B. Grossman, Yu-Feng Qiu, Yang Luo, Tian Lan, and Xing-Wei Yang. "" 2022, , 2845.
Nabin Panth, Eliott S. Wenger, Carsten Krebs, J. Martin Bollinger, Jr., and Robert B. Grossman. "" 2022, , e202200081.
Jingbo Sun, Zhonglin Wei, Robert B. Grossman, and Ran Lu. "" 2022, , 106.
Xiaohui Wang, Xiao-Bin Nie, Robert B. Grossman, Tengfei Ji, and Xing-Wei Yang. "" 2021, , 2059–2064.
Robert B. Grossman and Xing-Wei Yang. "" 2020, , 2041–2044.
Xing-Wei Yang and Robert B. Grossman. "." 2020, , 760–763.
Minakshi Bhardwaj, Qianxiang Ai, Sean R. Parkin, and Robert B. Grossman. "" 2020, , 77–81.
Juan Pan, Eliott Wenger, Megan Matthews, Christopher Pollock, Minakshi Bhardwaj, Amelia Kim, Benjamin Allen, Robert B. Grossman, Carsten Krebs, and J. Martin Bollinger, Jr. "" 2019, , 15153–15165.
S. E. Kearney, G. Zahoránszky-Kőhalmi, K. R. Brimacombe, M. J. Henderson, C. Lynch, T. Zhao, K. K. Wan, Z. Itkin, C. Dillon, M. Shen, D. M. Cheff, T. D. Lee, D. Bougie, K. Cheng, N. P. Coussens, D. Dorjsuren, R. T. Eastman, R. Huang, M. J. Iannotti, S. Karavadhi, C. Klumpp-Thomas, J. S. Roth, S. Sakamuru, W. Sun, S. A. Titus, A. Yasgar, Y.-Q. Zhang, J. Zhao, R. B. Andrade, M. K. Brown, N. Z. Burns, J. K. Cha, E. E. Mevers, J. Clardy, J. A. Clement, P. A. Crooks, G. D. Cuny, J. Ganor, J. Moreno, L. A. Morrill, E. Picazo, R. B. Susick, N. K. Garg, B. C. Goess, R. B. Grossman, C. C. Hughes, J. N. Johnston, M. M. Joullie, A. D. Kinghorn, D. G. I. Kingston, M. J. Krische, O. Kwon, T. J. Maimone, S. Majumdar, K. N. Maloney, E. Mohamed, B. T. Murphy, P. Nagorny, D. E. Olson, L. E. Overman, L. E. Brown, J. K. Snyder, J. A. Porco, Jr., F. Rivas, S. A. Ross, R. Sarpong, I. Sharma, J. T. Shaw, Z. Xu, B. Shen, W. Shi, C. R. J. Stephenson, A. L. Verano, D. S. Tan, Y. Tang, R. E. Taylor, R. J. Thomson, D. A. Vosburg, J. Wu, W. M. Wuest, A. Zakarian, Y. Zhang, T. Ren, Z. Zuo, J. Inglese, S. Michael, A. Simeonov, W. Zheng, P. Shinn, A. Jadhav, M. B. Boxer, M. D. Hall, M. Xia, R. Guha, J. M. Rohde. "" 2018, , 1727–1741.
Juan Pan, Minakshi Bhardwaj, Bo Zhang, Wei-chen Chang, Christopher L. Schardl, Carsten Krebs, Robert B. Grossman, and J. Martin Bollinger, Jr. "." 2018, , 2074–2083. article.
Xing-Wei Yang, Robert B. Grossman, and Gang Xu. "." 2018, , 3508-3558.
Juan Pan, Minakshi Bhardwaj, Padmaja Nagabhyru, Robert B. Grossman, and Christopher L. Schardl. "." 2014, 9(12), e115590.
Juan Pan, Minakshi Bhardwaj, Jerome R. Faulkner, Padmaja Nagabhyru, Nikki D. Charlton, Richard M. Higashi, Anne-Frances Miller, Carolyn A. Young, Robert B. Grossman, and Christopher L. Schardl. "." 2014, , 60–68.
Martin J. Spiering, Jerome R. Faulkner, Dong-Xiu Zhang, Caroline Machado, Robert B. Grossman, and Christopher L. Schardl. "." 2008, , 1307–1314.
Lynnette M. A. Dirk, Jack J. Schmidt, Yiying Cai, Jonathan C. Barnes, Katherine M. Hanger, Nihar R. Nayak, Mark A. Williams, Robert B. Grossman, Robert L. Houtz, and David W. Rodgers. "." 2008, , 417–427.
Christopher L. Schardl, Robert B. Grossman, Padmaja Nagabhyru, Jerome R. Faulkner, and Uma P. Mallik. "." 2007, , 980–996.
Roxana Ciochina and Robert B. Grossman. "." 2006, , 3963–3986.
Jerome R. Faulkner, Syed R. Hussaini, Jimmy D. Blankenship, Sitaram Pal, Bruce M. Branan, Robert B. Grossman, and Christopher L. Schardl. "." 2006, , 1078–1088.
Raghu Ram Chamala, Roxana Ciochina, Raphael A. Finkel, Robert B. Grossman, Saravana Kannan, and Prasanth Ramachandran. "." 2006, , 164–169.
Jimmy D. Blankenship, Justin B. Houseknecht, Sitaram Pal, Lowell P. Bush, Robert B. Grossman, and Christopher L. Schardl. "." 2005, , 1016–1022.
Jason T. Brewer, Sean Parkin, and Robert B. Grossman. "." 2004, , 591–594.
Roxana Ciochina and Robert B. Grossman. "." 2003, , 4619–4622.
Shuqian Liu, Hui Huang, Xin Lu, Miroslaw Golinski, Sébastien Comesse, David Watt, Robert B. Grossman, and Jeffrey A. Moscow. "." 2003, , 665–673.
Robert B. Grossman and Ravindra M. Rasne. "Methodology Validation and Structure Correction by Total Synthesis: The Case of the Clerodane Diterpenoid, Sacacarin." In Strategies and Tactics in Organic Synthesis; M. Harmata, Ed.; Elsevier: Amsterdam, 2004; Vol. 4, Chap. 1, pp. 1–18.
Kazuyuki Hattori and Robert B. Grossman. "." 2003, , 1409–1417.
Robert B. Grossman, Sébastien Comesse, Ravindra M. Rasne, Kazuyuki Hattori, and Matthew N. Delong. "." 2003, , 871–874.
Robert B. Grossman, Kazuyuki Hattori, Sean Parkin, Brian O. Patrick, and Melissa A. Varner. "." 2002, , 13686–13687.
Derrick S. Holeman, Ravindra M. Rasne, and Robert B. Grossman. "." 2002, , 3149–3151.
Robert B. Grossman and Ravindra M. Rasne. "." 2001, , 4027–4030.
Freddie Hughes, Jr. and Robert B. Grossman. "." 2001, , 2911–2914.
Robert B. Grossman. "." 2001 , 13–21.
Robert B. Grossman and Helen Jacobs. "." 2000, , 5165–5169.
Robert B. Grossman, Dhananjay S. Pendharkar, Ravindra M. Rasne, and Melissa A. Varner. "" 2000, , 3255–3258.
Robert B. Grossman, Aaron J. Skaggs, Arlene E. Kray, and Brian O. Patrick. "." 1999, , 1583–1586.
Melissa A. Varner and Robert B. Grossman. "." 1999, , 13867–13886.
Robert B. Grossman, Dhananjay S. Pendharkar, and Brian O. Patrick. "." 1999, , 7178–7183.
Robert B. Grossman, Ravindra M. Rasne, and Brian O. Patrick. "." 1999, , 7173–7177.
Robert B. Grossman, Melissa A. Varner, and Aaron J. Skaggs. "." 1999, , 340–341.
Robert B. Grossman. "." 1999, , 919–934.
Robert B. Grossman and Robert J. Trupp. "." 1998, , 1233–1237.
Robert B. Grossman and Melissa A. Varner. "." 1997, , 5235–5237.
Robert B. Grossman. "." 1997, , S1430-4171(97)02117-1.
Robert B. Grossman. "." 1997, , 1906–1908.

Books and Software:

Robert B. Grossman. , .
- 1st ed., 1999.
- 2nd ed., 2002.
- 3rd ed., 2019.
: a Web-based organic chemistry homework program that provides response-specific feedback to structures drawn by students.

Research papers prior to independent career:

Alasdair J. Nisbet, A. Jennifer Mordue (Luntz), Robert B. Grossman, Lyn Jennens, Steven V. Ley, and William Mordue. "." 1997, , 461-473, and 2001, , 78-86.
Mariluz L. de la Puente, Robert B. Grossman, Steven V. Ley, Monique S. J. Simmonds, and Wally M. Blaney. "." 1996, , 1517-1521.
Monique S. J. Simmonds, Wally M. Blaney, Steven V. Ley, James C. Anderson, Rolf Bänteli, Alastair A. Denholm, P. Green, Robert B. Grossman, Clare Gutteridge, Lynn Jennens, Stephen C. Smith, Peter L. Toogood, and Anthony Wood. "." 1995, , 69-80.
Monique S. J. Simmonds, Wally M. Blaney, Robert B. Grossman, and Steven V. Ley. "." 1995, , 555-564.
Robert B. Grossman and Steven V. Ley. "." 1994, , 11553-11568.
Robert B. Grossman and Steven V. Ley. "." 1994, , 8871-8884.
Robert B. Grossman, Jing-Cherng Tsai, William M. Davis, Alberto Gutiérrez, and Stephen L. Buchwald. "." 1994, , 3892-3896.
Scott C. Berk, Robert B. Grossman, and Stephen L. Buchwald. "." 1994, , 8593-8601.
Scott C. Berk, Robert B. Grossman, and Stephen L. Buchwald. "." 1993, , 4912-4913.
Robert B. Grossman and Stephen L. Buchwald. "." 1992, , 5803-5805.
Robert B. Grossman, William M. Davis, and Stephen L. Buchwald. "." 1991, , 2321-2322.
Robert B. Grossman, Ruth Ann Doyle, and Stephen L. Buchwald. "." 1991, , 1501-1505.
Keith A. Horn, Robert B. Grossman, Jonathan R. G. Thorne, and Anne A. Whitenack. "." 1989, , 4809-4821.
Robert B. Grossman. "." 1989, , 30-33.
Robert A. Pascal, Jr., Robert B. Grossman, and Donna van Engen. "." 1987, , 6878-6880.
Robert A. Pascal, Jr. and Robert B. Grossman. "." 1987, , 4616-4617.
Keith A. Horn, Robert B. Grossman, and Anne A. Whitenack. "." 1987, , 271-278.