Mass spectrometry research in my group is divided into three broad areas: 1) mass spectrometry based "Omic" sciences 2) analytical methods development in chemistry and biology and 3) instrument development.
In the 鈥淥mics鈥 area, we are currently working in proteomics, lipidomics and metabolomics. We continue our efforts to utilize proteomics to elucidate protein changes associated with protozoa infections, neuronal diseases such as Alzheimer鈥檚 disease and microbial solventogenesis in biofuels production. We are also working on metabolic profiles from easily obtainable biological fluids using capillary electrophoresis mass spectrometry.
Methods development has been expanded to include biofuels and forensic problems. We are currently developing methods to elucidate changes in lignin composition during biomass pretreatment, synthesizing model lignin oligomers and utilizing tandem mass spectrometry to identify monolignol composition and bonding. Additionally, we are exploring the use of solid phase microextraction with GC/MS and paper spray mass spectrometry to characterize and quantify organic gunshot residue.
A variety of instrument development projects are underway including development of alternative API ionization schemes (inlet ionization) and novel CE/MS interfaces.
Analytical 九色视频, Mass Spectrometry
Omics and Biomarkers
Biomass
